According to the research of Harry Stanz,2298 Samuel Hammond was born in Fairfax Co VA. He received a pension for service in the Revolutionary War. The family apparently lived in Warren and Granville Counties NC and moved to Kershaw Co SC in 1782-84. About 1810 he took his family west to the Mississippi Territory and settled in the area that became Clarke Co AL. With him on the trek to Alabama were sons Samuel Sims, Lemuel, Sherwood, Mathias and William Raleigh and daughters Elizabeth, Charlotte, Mary and Sarah, all of whom married in Alabama.

Samuel Hammond and his family relocated from Kershaw Co to the Tombigbee River area of the Mississippi Territory in 1808. He is listed on the 1810 census of the Mississippi Territory, as is his son Mathias.2299

Samuel Hammond patented land in Sumter Co AL on 8/1/1837:

40 acres S½SW Section 32 Township 17-N Range 2-W St Stephens Meridian, AL Sumter 
160 acres NE Section 21 Township 17-N Range 2-W St Stephens Meridian, AL Sumter
80 acres E½SE Section 31 Township 17-N Range 2-W St Stephens Meridian, AL Sumter

Samuel Hammond was not located in the 1830 census.

1840 Census of Sumter Co AL

Saml Hammond 1 M 80-90 [listed next to Sherrod Hammond and near Samuel, Matthias & Wm Hammond] It is noted on the census record that he was 88 years of age and a pensioner for Revolutionary War service.

There is a monument to him in the Hammond Cemetery in Kershaw Co. The cemetery is on the Kershaw-Lancaster county line, between Heath Springs and Stonsboro. It is about two miles south of Baeyer Creek Baptist Church.2298 The inscription on the monument reads:2301

Samuel Hammond
Son of Samuel and Mary Hammond
Born 9th Nov., 1753
Died 18th August, 1844

There has been debate about Samuel Hammond’s wife or wives. Most sources give the name of the mother of most or all of his children as Frances Sims. Following is a good summary of other suggestions:2299

“The exact identity of the wife or wives of Samuel Hammond is debatable. One family historian argues that he was married to Winifred Sims, daughter of Sherwood Sims a family friend and witness to Capt Sam's will. They assert this claim by mentioning that one of Sam Jr's sons was named Sherwood/Sherrod and another son may have had the middle name of Sims. Another family historian goes one step further and claims Sam Jr was married twice, the first one being named Winnifred Jenkins with whom he had a son named John, the second being Frances Sims. Another contends that he was married to Winnifred Twitty, descendant of Peter Twitty. Still another group claims that this woman was Native American of Choctaw heritage. While it is VERY possible that Sam was married multiple times, I have seen no official documented evidence backing any one of these claims. I found no evidence of death records or burial sites in AL for any of these women.

According to Mr Harry Stanz in his publication "The HAMMOND Family of Sumter and Marengo Counties, Alabama":
Samuel was married to Winifred Sims b abt 1760 in Granville Co NC or VA

Another Hammond researcher, contends:
"Samuel first married Winnifred Jenkins. They had one child: John. Samuel second married Frances Sims." He didn't list any children from the marriage of Frances and Samuel.

It is certain that the first name of at least one of Samuel’s wives was Winnifred. The following tombstone monument is found in the Old Hammond Family Cemetery, near Heath Springs SC:2301

TWITTY
Winnifred Twitty
Daughter of Samuel
and Winnifred Hammond
Born 8th April 1784
Died June, 1839

It was also clear that Samuel had a wife before Winnifred that was named Mary, because another of his sons is buried in the same cemtery with the following tombstone inscription:

HAMMOND
Sacred
to the memory of
John Hammond, Senior
son of Samuel and Mary Hammond
born the 1st January A. D. 1779
Was baptized the 1st October 1840
....(stone broken)

Note added 21 November 2016 by Clayton Heathcock:

Saml Hammond married Francis Simms in Warren Co NC. Bondsman was Rawleigh Hammond and Witness was M. D. Johnson. Unfortunately, the date of this marriage is obscured and not readable.2305